Wednesday, August 17, 2011

beta blockers in COPD

It has been a looong gap ....moving and starting a fellowship in a new place is a little tough. Anyway I have settled down in my new place now. 
Let me start with a short blog..regarding a discussion between a pulmonary fellow and the primary team that I happened to hear while doing my usual hyponatremia consult!
Traditionally betablockers were not used in patients with COPD or asthma due to bronchospam. But using a cardioselective agent may not afect the airways.But a recent retrospective study in bmj went a step ahead and showed that it may be even beneficial in patients with COPD. 
Of nearly 6000 patients with different stages of COPD ,they found that there was a 22% reduction in all cause mortality from beta blockers. The benifit was shown across all stages of COPD. With regards to lung function, they did not affect FEV1/FVC. also betablockers seemed to have additive benifits on hospital admissions. This benifit was seen independent of presence of cardiovascular disease.

Figure


A somewhat related study published by one of my senior resident(Int J Chron Obst Pulm Disease 2010)  showed that patients with COPD may have unrecognised myocardial injury. May be betablockers help with this and this is what we are seeing here. 
Time to change practice!!

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  33. maggie.danhakl@healthline.comApril 11, 2014 at 7:56 AM

    Hi,

    Healthline just launched a campaign for called "You Are Not Your COPD" where COPD patients share their story or advice about living with the disease. You can see the homepage for the campaign here: http://www.healthline.com/health/copd/inspirational-stories

    We have partnered with the COPD Foundation to promote the campaign and have pledged that for every submitted story, Healthline will donate $10 to the COPD Foundation.

    I am writing to ask if you can help spread the word about this campaign by including it as a resource on your page: http://medicineforresidents.blogspot.com/2011/08/beta-blockers-in-copd.html

    The more stories we receive the more Healthline will donate to COPD research, support, and treatment programs. Would you please consider including this on your site or sharing with your followers?

    I'm happy to answer any questions you may have.

    Thank you,
    Maggie Danhakl • Assistant Marketing Manager
    p: 415-281-3124 f: 415-281-3199

    Healthline • The Power of Intelligent Health
    660 Third Street, San Francisco, CA 94107
    www.healthline.com | @Healthline | @HealthlineCorp

    About Us: corp.healthline.com

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